Posttransfusion thrombocytopenia associated with passive transfusion of a platelet‐specific antibody
Identifieur interne : 003242 ( Main/Exploration ); précédent : 003241; suivant : 003243Posttransfusion thrombocytopenia associated with passive transfusion of a platelet‐specific antibody
Auteurs : E. P. Scott [États-Unis] ; J. Moilan-Bergeland ; A. P. DalmassoSource :
- Transfusion [ 0041-1132 ] ; 1988-01-02.
Abstract
A transfusion reaction in a 76‐year‐old man was followed by severe but transient thrombocytopenia after infusion of whole blood. A high‐titer platelet‐specific antibody (anti‐PLA) was demonstrated in the plasma of the implicated unit and in the serum of the blood donor. In addition, three previous recipients of blood from the implicated donor had posttransfusion episodes of unexplained thrombocytopenia. These cases represent the first reported clinical examples of posttransfusion thrombocytopenia caused by passively transfused platelet‐specific alloantibodies.
Url:
DOI: 10.1046/j.1537-2995.1988.28188127960.x
Affiliations:
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<author><name sortKey="Moilan Ergeland, J" sort="Moilan Ergeland, J" uniqKey="Moilan Ergeland J" first="J." last="Moilan-Bergeland">J. Moilan-Bergeland</name>
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<wicri:cityArea>Correspondence address: Edward P. Scott, Department of Laboratory Medicine and Pathology, and Assistant Medical Director, Blood Bank, University of Minnesota Hospital, Minneapolis, Minnesota, and Associate Medical Director, American Red Cross Blood Services, St. Paul Region, St. Paul</wicri:cityArea>
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<front><div type="abstract" xml:lang="en">A transfusion reaction in a 76‐year‐old man was followed by severe but transient thrombocytopenia after infusion of whole blood. A high‐titer platelet‐specific antibody (anti‐PLA) was demonstrated in the plasma of the implicated unit and in the serum of the blood donor. In addition, three previous recipients of blood from the implicated donor had posttransfusion episodes of unexplained thrombocytopenia. These cases represent the first reported clinical examples of posttransfusion thrombocytopenia caused by passively transfused platelet‐specific alloantibodies.</div>
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